Environment impacts aging at a genetic level

The places we live can change us -- in many cases, down to the molecular level. Exposure to chemicals and other harmful substances in our environment can affect our health in myriad ways over time, aggravating existing health problems, contributing to new disease such as cancer and even impacting how our genes work. Scientists are studying the way our genomic and biological processes change in response to the environment or other external factors in the growing field of epigenetics. In a pair of 2020 studies, [scientists from the United States Environmental Protection Agency (EPA)] found that 1) epigenetic changes related to aging and mortality are impacted by the environment, and 2) epigenetic changes may reveal whether a person is more susceptible to health risks in their environment. The studies are among the first to link these biological indicators of accelerated aging, called molecular biomarkers, to both the quality of the environment and environmental health risks. [Reprinted from the US Environmental Protection Agency's Science Matters newsletter, April 19, 2021.]